Protein Purification Reagents and Kits
BIOHIPPO h/m BCL-xL-sh-RFP-Puro
h/m BCL-xL-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m BCL-xL shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse BCL2 like 1 (BCL-xL) The shRNA has been validated to meet or exceed 70% BCL-xL knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Abcam BVT 948, Protein tyrosine phosphatase (PTP) inhibitor, 10MG
MW 241.24 Da, Purity >99%. Non-competitive, irreversible protein tyrosine phosphatase (PTP) inhibitor (IC₅₀ values are 0.9 (PTP1B), 1.7 (TCPTP), 0.09 (SHP-2), 1.5 (LAR) and 0.7 (YopH) μM). Active in vivo and cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend KIRAVIA Blue 520TM anti-mous
KIRAVIA Blue 520™ anti-mouse CD366 (Tim-3) [RMT3-23]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 25 ug
Amsbio LLC Immunoplate for capture L1CAM positive exosomes
Immunoplate for capture L1CAM positive exosomes
MONOD BIO INC The NovoBody™ Duo Fc is a tetravalent single-chain binder targeting the DYKDDDDK tag, with a human Fc fused to the C-terminus. It is ideal in applications for binding where a human Fc is required.
Anti-DYKDDDDK Tag NovoBody™ Duo, Human IgG1 Fc. The NovoBody™ Duo Fc is a tetravalent single-chain binder targeting the DYKDDDDK tag, with a human Fc fused to the C-terminus. It provides substantially higher affinity than conventional anti-DYKDDDDK antibodies and is ideal for applications requiring strong binding where a human Fc is required. NovoBody™ Binders are single-chain proteins designed computationally to improve on traditional antibodies. They offer enhanced stability and function while eliminating suboptimal traits like post-translational modifications. The Duo Fc is suitable for ELISA, Western Blot, flow cytometry, BLI, and capture applications. Tag: Human IgG1 Fc | Conjugation: None | Amount: 100 µg. Learn more at monod.bio
Cayman Chemical NavenI PD1PD-L1 Ato647N 100RXN
A metabolite of bortezomib a degradation product of bortezomib formed under oxidative conditions
AdipoGen PARP-1 E988K Mutant Ctrl
Protein. Human full-length inactive mutant E998K of PARP-1 is fused to a HA-tag and a His-tag. Source Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. Purity >95% SDS-PAGE. PARP-1 ARTD1 is involved in the base excision repair BER pathway, by catalyzing the polyADP-ribosylation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 Th1 cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Cayman Chemical NavenIFlex TIsue MR RED 100RXN
A metabolite of isoleucine induces the formation of TBARS in isolated rat cerebral cortex at 0.5-5 mM elevated levels of are associated with 2-MBCDD also known as SBCAD
Active Motif MeDIP
The MeDIP Kit is designed to immunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC). The MeDIP Kit contains a monoclonal 5-methylcytidine antibody, a bridging antibody and the necessary buffers to perform methylated DNA immunoprecipitation (MeDIP). The affinity of the antibody enables separation of 5-mC DNA from 5-hmC DNA using single-stranded input DNA. Active Motif's fast, magnetic protocol has been streamlined to minimize the number of wash and incubation steps, saving you valuable time. The kit also includes MseI digested human genomic DNA and PCR primers that can be used to verify the efficiency of the enrichment. Additionally, the kit contains a bar magnet for easy separation and elution of the enriched methylated DNA.
Revvity Health Sciences Inc Glycan Profiling Assay Release and Labeling Kit
Glycan Profiling Assay Release and Labeling Kit
STEMCELL Technologies EasySep™ Human Memory CD8+ T Cell Enrichment Kit, For processing: 1 x 10^9 cells
The EasySep™ Human Memory CD8+ T Cell Enrichment Kit is designed to isolate memory CD8+ T cells from peripheral blood mononuclear cells by negative selection. Unwanted cells are targeted for removal with antibody complexes recognizing CD4, CD14, CD16, CD19, CD20, CD34, CD36, CD45RA, CD56, CD61, CD66b, CD123, TCRγ/δ, glycophorin A and dextran-coated magnetic particles. The labeled cells are separated using an EasySep™ magnet without the use of columns. Desired cells are poured off into a new tube.
American Research Products Inc Mouse B and T lymphocyte atte
Mouse B- and T-lymphocyte attenuator (BTLA) ELISA kit from CUSABIO Detection Range 0 625 ng/mL-40 ng/mL Sensitivity 0 156 ng/mL Sample serum plasma tissue homogenates Method Sandwich
STEMCELL Technologies RoboSep™ HLA Chimerism Whole Blood CD66b Positive Selection Kit, For processing: 60 mL whole blood processed
The EasySep™ HLA Chimerism Whole Blood CD66b Positive Selection Kit is designed to isolate highly purified CD66b+ cells from fresh whole blood by positive selection. Desired cells are targeted with Tetrameric Antibody Complexes recognizing CD66b and dextran-coated magnetic particles. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off. The CD66b antigen is expressed on mature granulocytes. Isolated cells are immediately available for downstream applications such as flow cytometry, culture, or DNA/RNA extraction for lineage-specific chimerism analysis.This product replaces the EasySep™ Human Whole Blood CD66b Positive Selection Kit (Catalog #18682) for even faster cell isolations.